I think it will be a hell of a game that either team could win. I may give JF a slight advantage because they are at home. JF is a school that has good fan support and a somewhat unique stadium environment that provides a bit of intimidation.
Both teams have been at the top of the heap and slipped back in recent years. They both have made great strides recently and are hungry for more.
I think the question is who is going to settle for just making it to the Regional semifinals, and who is more determined to go further?